- Full Potency
- In Foil Blister Pack
- Natural
- pH Sensitive
- Food Grade
- Enteroguard Coating
- S-Adenosyl Methionine
- 400 mg (Net Yield) SAM-e from 800 SAM-e tosylate Didulfate
- Highest Concentration of Active S,S Form
- Enteric-Coated Tablets
- Net Yield -400 Mg SAM-e
- Gluten Free
- Vegan
- Dietary Supplement
Promotes:
- Joint Strength
- Liver Detoxification
- Mood and Brain Function
Jar Formulas SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jar Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
Joint Strength
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are componenets of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.
EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper instestines, where the SAMe is made available for absorption.
